Ought to Human Milk-Primarily based Dietary Merchandise for Untimely Infants Be Homogenized? Extra Analysis Is Wanted, New Journal Article Says

DUARTE, Calif., March 23, 2022 /PRNewswire/ — Prolacta Bioscience®, the world’s main hospital supplier of 100% human milk-based dietary merchandise for untimely, critically in poor health infants, introduced right this moment the publication of a journal article that summarizes present proof on the affect of homogenization on human milk-based dietary merchandise. The article focuses on modifications to the macromolecular construction of the milk fats globule (MFG) and the following affect on digestion and was printed in December within the peer-reviewed journal Present Developments in Vitamin.1

Ought to Human Milk-Primarily based Dietary Merchandise for Untimely Infants Be Homogenized? Extra Analysis Is Wanted, New Journal Article Says

(PRNewsfoto/Prolacta Bioscience)

Authored by Sarah M. Reyes, Ph.D., MSc, and colleagues, “The Impression of Homogenization on Donor Human Milk and Human Milk-Primarily based Fortifiers and Implications for Preterm Toddler Well being” makes use of printed knowledge to create a conceptual framework for the potential implications of homogenized human milk-based dietary merchandise on preterm toddler well being and suggests avenues for future analysis.

“Homogenization disrupts the milk fats globule, which can result in untimely digestion of bioactive parts, together with sphingolipids and long-chain polyunsaturated fatty acids (LCPUFAs), linked to favorable neurological outcomes. The implications of those modifications for toddler well being are unknown,” in accordance with Reyes, scientific liaison, human milk and medical analysis, at Prolacta.

Homogenization is a course of that evenly disperses two liquids to create a single uniform combination. Within the dairy business, homogenization is used to enhance cow milk’s style, consistency, and look, in addition to to increase its shelf life. Dairies homogenize cow milk to disperse fats droplets and stop the cream from rising to the highest.

Human milk is a posh, dynamic bioactive fluid with a myriad of compounds that make it the popular vitamin for infants to help their immunity, development, neurodevelopment,2 and total long-term well being.3

“The well-established medical advantages of human milk-based dietary merchandise solely apply to at present out there non-homogenized merchandise. The security and efficacy of homogenized human milk-based dietary merchandise haven’t been established,” Reyes wrote.

“Human milk-based dietary merchandise will not be created equally,” stated Melinda Elliott, chief medical officer for Prolacta, training neonatologist, and a research co-author. “As human milk researchers and medical professionals, it’s our opinion that the usage of industrial processing strategies corresponding to homogenization, with or with out high-heat processing, must be averted for human milk-based dietary merchandise till their security and efficacy have been established.”

About Human Milk-Primarily based Merchandise
The key distinction between cow milk-based and human milk-based merchandise is the composition — notably, the bioactive parts which might be distinctive to human milk. These embody immunoglobulins, lactoferrin, milk fats globule membrane, and the vast spectrum of prebiotics often known as human milk oligosaccharides (HMOs), which aren’t simply manufactured and thus are enormously decreased or lacking from cow milk-based dietary merchandise.4 Bioactivity is believed to help infants’ immunity, growth, development, and long-term well being.2

Prolacta’s 100% human milk-based dietary merchandise have the best bioactivity within the human milk business.5 Prolacta’s dietary merchandise are vat pasteurized utilizing profiles outlined by the U.S. Meals and Drug Administration (FDA) to make sure pathogen inactivation and the best stage of security whereas retaining as a lot of the pure bioactivity of the milk as doable.5 Prolacta’s vat pasteurized merchandise retain greater bioactivity than merchandise processed utilizing different strategies, together with retort sterilization and ultra-high-temperature (UHT) processing.6,7

About Prolacta Bioscience
Prolacta Bioscience® Inc. is a privately held, world life sciences firm devoted to Advancing the Science of Human Milk® to enhance the well being of untimely, critically in poor health infants. Prolacta’s 100% human milk-based dietary merchandise have been evaluated in additional than 20 medical research printed in peer-reviewed journals. Greater than 80,000 untimely infants have benefited from Prolacta’s dietary merchandise worldwide to this point.8 Established in 1999, Prolacta is the world’s main supplier of human milk-based dietary merchandise for hospital use and can also be exploring the therapeutic potential of human milk throughout a large spectrum of ailments. Prolacta maintains the business’s strictest high quality and security requirements for screening, testing, and processing donor human milk. Working the world’s first pharmaceutical-grade human milk processing services, Prolacta makes use of vat pasteurization and a patented, FDA-reviewed manufacturing course of to make sure pathogen inactivation whereas defending the dietary composition and bioactivity of its human milk-based merchandise. Prolacta is a worldwide firm with headquarters in Duarte, California, and will be discovered on-line at www.prolacta.com, on Twitter, Instagram, Fb, and LinkedIn.

Media Contact:
Loren Kosmont
[email protected]
310-721-9444

References

  1. Reyes SM, Patra B, Elliott MJ. The affect of homogenization on donor human milk and human milk-based fortifiers and implications for preterm toddler well being. Curr Dev Nutr. Printed on-line December 8, 2021. https://doi.org/10.1093/cdn/nzab147

  2. Gila-Diaz A, Arribas SM, Algara A, Martín-Cabrejas MA, López de Pablo ÁL, Sáenz de Pipaón M, Ramiro-Cortijo D. A evaluation of bioactive elements in human breastmilk: a deal with prematurity. Vitamins. 2019;11(6):1307. doi:10.3390/nu11061307

  3. American Academy of Pediatrics. Breastfeeding and the usage of human milk. Part on Breastfeeding. Pediatrics. 2012;129(3):e827-e841. doi:10.1542/peds.2011-3552

  4. Ballard O, Morrow AL. Human milk composition: vitamins and bioactive elements. Pediatr Clin North Am. 2013 Feb;60(1):49-74. doi: 10.1016/j.pcl.2012.10.002. PMID: 23178060; PMCID: PMC3586783.

  5. Knowledge on file.

  6. Meredith-Dennis L, Xu G, Goonatilleke E, Lebrilla CB, Underwood MA, Smilowitz JT. Composition and variation of macronutrients, immune proteins, and human milk oligosaccharides in human milk from nonprofit and business milk banks. J Hum Lact. 2018;34(1):120-129. doi:10.1177/0890334417710635

  7. Lima HK, Wagner-Gillespie M, Perrin MT, Fogleman AD. Micro organism and bioactivity in Holder pasteurized and shelf-stable human milk merchandise. Curr Dev Nutr. 2017;1(8):e001438. doi:10.3945/cdn.117.001438

  8. Estimated variety of untimely infants fed Prolacta’s merchandise from January 2007 to December 2021; knowledge on file.

Cision

Cision

View unique content material to obtain multimedia:https://www.prnewswire.com/news-releases/should-human-milk-based-nutritional-products-for-premature-infants-be-homogenized-more-research-is-needed-new-journal-article-says-301508329.html

SOURCE Prolacta Bioscience